If these are not compatible with a brother or Dymo printers do they work with Zebra? or Any other big brands I can look into? Thanks

The RL2961TT can be used with Zebra thermal transfer printer models that allow for a 1" core and 4" outer diameter. If using another brand, you'll want to check the thermal transfer printer's specifications to ensure that it allows for gap sensing in addition to the stated core and outer diameter sizes.

I am wondering about the difference between direct thermal and thermal transfer? Also, I want a more "permanent" stick. I purchased the standard thermal transfer last time. Can you advise me as to if the weatherproof thermal transfer might have a better adhesion? thanks!

The difference between direct thermal and thermal transfer is that the thermal transfer printers require a ribbon. If you're using a thermal transfer printer and would like a more durable material with an aggressive adhesive, the Weatherproof Thermal Transfer should work well for you. Please note that when using the polyester-based weatherproof material, you will need a durable wax resin ribbon. You can visit the following link to view our available ribbons, https://www.onlinelabels.com/uses/thermal-ribbons . If you need assistance with finding one compatible with your printer, please feel free to reach out to Customer Support at 888-575-2235 with the make and model of your printer. You can visit the link below to request free samples of this material for testing with your application. https://www.onlinelabels.com/samples